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Clinical Trial Design: Bayesian and Frequentist Adaptive Methods

Guosheng Yin




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 | #209663 in Books |  2012-01-03 | Original language:English | PDF # 1 |  9.60 x.94 x6.42l,1.40 | File type: PDF | 364 pages

|| ||“In summary, this book is useful for anyone interested in design and analysis of clinical studies. The main strengths of this book are the well-balanced approach between statistical theories and statistical analysis methods of the design issues involved

A balanced treatment of the theories, methodologies, and design issues involved in clinical trials using statistical methods

There has been enormous interest and development in Bayesian adaptive designs, especially for early phases of clinical trials. However, for phase III trials, frequentist methods still play a dominant role through controlling type I and type II errors in the hypothesis testing framework. From practical perspectives, Clinical...

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