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Phosphodiesterase Inhibitors (Handbook of Immunopharmacology)

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 | #6086834 in Books |  1996-09-10 | Original language:English | PDF # 1 |  10.25 x7.75 x.75l,1.49 | File type: PDF | 228 pages

||From the Back Cover|Non-selective inhibitors of cyclic nucleotide phospho-diesterase (PDE), such as theophylline, have been in clinical use since the last century and have been used extensively in research since the identification of PDE in 1958.|Various PDE iso

Non-selective inhibitors of cyclic nucleotide phosphodiesterase (PDE), such as theophylline, have been used extensively since 1958. In the decade of the '70s, various PDE isoenzymes were defined which led to the development of the second generation of PDE inhibitors. Currently a variety of these new inhibitors are under test as potential anti-inflammatory drugs. During the past five years, molecular biology has revealed a superfamily of these phosphodiesterase isoenzymes...

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